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Epidemiology of chikungunya : ウィキペディア英語版
Epidemiology of chikungunya

A number of chikungunya outbreaks have occurred since 2005. An analysis of the chikungunya virus's genetic code suggests that the increased severity of the 2005–present outbreak may be due to a change in the genetic sequence, altering the virus' viral coat protein, which potentially allows it to multiply more easily in mosquito cells.〔 The change allows the virus to use the Asian tiger mosquito (an invasive species) as a vector in addition to the more strictly tropical main vector, ''Aedes aegypti''. In July 2006, a team analyzed the virus' RNA and determined the genetic changes that have occurred in various strains of the virus and identified those genetic sequences which led to the increased virulence of recent strains.
==2005–06: Réunion==
The largest outbreak of chikungunya ever recorded at the time occurred on the island of Réunion in the western rim of the Indian Ocean from late March 2005 to February 2006.〔(【引用サイトリンク】url=http://www.promedmail.org/direct.php?id=2209285 )〕 At its height, the incidence peaked at about 25,000 cases per week or 3500 daily in early 2006. After an initial peak in May 2005, the incidence decreased and remained stable through the summer hemisphere winter, rising again at the beginning of October 2005. By mid-December, when southern hemisphere summer temperatures are favorable for the mosquito vector, the incidence began to rise dramatically into the first two months of 2006.〔(【引用サイトリンク】url=http://www.promedmail.org/direct.php?id=2209201 )〕 The number of reported cases was thought to be underestimated. The French government sent several hundred troops to help eradicate mosquitoes. Although confirmed cases were much lower, some estimates based on extrapolations from the number detected by sentinel physicians suggested that as many as 110,000 of Réunion's population of 800,000 people may have been infected.〔(【引用サイトリンク】url=http://www.promedmail.org/direct.php?id=2209344 )〕 Twelve cases of meningoencephalitis cases were confirmed to be associated with chikungunya infection. Other countries in the southwest Indian Ocean reported cases as well, including Mauritius and the Seychelles,〔(Chikungunya in La Réunion Island (France) ), World Health Organization, 17 February 2006〕 and in Madagascar, the Comoros, and Mayotte.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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